OCAM/NCAM2 Protein, Human (HEK293, His)

OCAM/NCAM2 proteins are potential key players in selective fasciculations and interregional projections in olfactory axons. Its specific mechanism and functional significance in guiding axonal development remain to be further elucidated. OCAM/NCAM2 Protein, Human (HEK293, His) is the recombinant human-derived OCAM/NCAM2 protein, expressed by HEK293 , with C-His labeled tag.

OCAM/NCAM2 Protein emerges as a potential key player, indicating its critical roles in selective fasciculation and zone-to-zone projection of primary olfactory axons. The specific mechanisms through which OCAM/NCAM2 contributes to these intricate processes remain to be fully elucidated, prompting further investigation into its functional significance in guiding the development and projection of olfactory axons. The proposed involvement of OCAM/NCAM2 in selective fasciculation underscores its potential impact on the formation of defined axonal bundles, while its role in zone-to-zone projection suggests a regulatory influence on the spatial organization of olfactory axons within distinct regions. The nuanced functions proposed for OCAM/NCAM2 highlight its significance in shaping the intricate neural circuitry associated with the primary olfactory system. Further research is essential to unravel the precise molecular pathways through which OCAM/NCAM2 orchestrates these crucial developmental events.

Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast cancer cells. The ED₅₀ for this effect is 0.5143 μg/mL, corresponding to a specific activity is 1944.39 units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast cancer cells. The ED₅₀ for this effect is 0.5143 μg/mL, corresponding to a specific activity is 1944.39 units/mg.

Human

HEK293

C-His

O15394-1/NP_004531.2 (L20-N697)

4685  [NCBI]

Extracellular Domain

LLQVTISLSKVELSVGESKFFTCTAIGEPESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFN

Approximately 90.1 kDa,based on SDS-PAGE under reducing conditions.

≥ 95%, as determined by reducing SDS-PAGE.

Solution

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.