2. Gene
  3. NCAM2 - neural cell adhesion molecule 2 Gene

NCAM2 - neural cell adhesion molecule 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NCAM21

Gene ID: 4685 | Gene type: protein coding

About NCAM2

Cytogenetic location: 21q21.1 Genomic coordinates (GRCh38): 21:20,998,409-21,543,329 (from NCBI)

This gene has 5 transcripts (splice variants), 217 orthologues and 36 paralogues. Biased expression in brain (RPKM 13.1), adrenal (RPKM 3.2) and 3 other tissues.

Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons. [provided by RefSeq, Jul 2008]

NCAM2 Products(8)

mRNA Protein Name
NM_001352591.2 NP_001339520.1 neural cell adhesion molecule 2 isoform 1 precursor
NM_001352592.2 NP_001339521.1 neural cell adhesion molecule 2 isoform 3
NM_001352593.2 NP_001339522.1 neural cell adhesion molecule 2 isoform 4 precursor
NM_001352594.2 NP_001339523.1 neural cell adhesion molecule 2 isoform 5 precursor
NM_001352595.2 NP_001339524.1 neural cell adhesion molecule 2 isoform 6 precursor
NM_001352596.2 NP_001339525.1 neural cell adhesion molecule 2 isoform 7 precursor
NM_001352597.2 NP_001339526.1 neural cell adhesion molecule 2 isoform 8
NM_004540.5 NP_004531.2 neural cell adhesion molecule 2 isoform 2 precursor

NCAM2 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (22 - 111)

I-set

I-set: Immunoglobulin I-set domain (117 - 191)

I-set

I-set: Immunoglobulin I-set domain (213 - 298)

I-set

I-set: Immunoglobulin I-set domain (306 - 396)

I-set

I-set: Immunoglobulin I-set domain (414 - 488)

fn3

fn3: Fibronectin type III domain (497 - 581)

fn3

fn3: Fibronectin type III domain (595 - 677)

  • 0
  • 200
  • 400
  • 600
  • 837 a.a.
Protein Preferred Names Protein Names

neural cell adhesion molecule 2

N-CAM-2

Recombinant NCAM2 Proteins

Cat. No. Product Name Accession Purity
HY-P76505 OCAM/NCAM2 Protein, Human (HEK293, Fc) O15394 (M1-N697) ≥95%
HY-P76506 OCAM/NCAM2 Protein, Human (HEK293, His) O15394 (M1-N697) ≥95%

Related Diseases

Diseases Alias
Lissencephaly 3

LIS3

Lissencephaly Due To Tuba1a Mutation

Lissencephaly Type 3

Lissencephaly, Type 3
Epilepsy, Familial Temporal Lobe, 7

Familial Temporal Lobe Epilepsy 7

ETL7

Epilepsy, Temporal Lobe, Familial, Type 7
Spinocerebellar Ataxia 37

Spinocerebellar Ataxia Type 37

SCA37

Spinocerebellar Ataxia With Altered Vertical Eye Movements
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09064 NCAM2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NCAM2 VGNC VGNC:43637
Bos taurus NCAM2 VGNC VGNC:31899
Felis catus NCAM2 VGNC VGNC:68422
Rattus norvegicus NCAM2 RGD RGD:1303131
Macaca mulatta NCAM2 VGNC VGNC:75137
Mus musculus NCAM2 MGD MGI:97282
Others NCAM2 NCBI