RALY - RALY heterogeneous nuclear ribonucleoprotein Gene
Also Known as P542; HNRPCL2
Species: Homo sapiens
About RALY
This gene has 10 transcripts (splice variants), 203 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 18.7), testis (RPKM 18.3) and 25 other tissues.
Summary
This gene encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) gene family. This protein may play a role in pre-mRNA splicing and in embryonic development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
RALY Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_007367.4 | NP_031393.2 | RNA-binding protein Raly isoform 2 |
| NM_016732.3 | NP_057951.1 | RNA-binding protein Raly isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22365833 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of catalytic step 2 spliceosome |
IDA
IDA: Inferred from direct assay
|
11991638 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
22720776 | GOA |
RALY Protein Structure
RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (23 - 85)
- 0
- 100
- 200
- 306 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
RNA-binding protein Raly |
|
RALY Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
RALY | Q9UKM9 | HNRNPC | Homo sapiens | P07910 | 30021884 | |
|
Intra
|
RALY | Q9UKM9 | HNRNPC | Homo sapiens | P07910 | 22365833 | |
|
Intra
|
RALY | Q9UKM9 | HNRNPC | Homo sapiens | P07910 | 33961781 | |
|
Intra
|
RALY | Q9UKM9 | FUS | Homo sapiens | P35637 | 30354839 | |
|
Intra
|
RALY | Q9UKM9 | FUS | Homo sapiens | P35637 | 30354839 | |
|
Intra
|
RALY | Q9UKM9 | FUS | Homo sapiens | P35637 | 30354839 | |
|
Intra
|
RALY | Q9UKM9 | HNRNPCL2 | Homo sapiens | B2RXH8 | 30021884 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Skin Carcinoma In Situ |
|
|
| Bardet-Biedl Syndrome 1 |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | RALY | MGD | MGI:97850 |
| Bos taurus | RALY | VGNC | VGNC:33706 |
| Rattus norvegicus | RALY | RGD | RGD:1307228 |
| Canis familiaris | RALY | VGNC | VGNC:45337 |
| Felis catus | RALY | VGNC | VGNC:81167 |
| Macaca mulatta | RALY | VGNC | VGNC:76486 |
| Others | RALY | NCBI |