Angeloylbinankadsurin A
Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM). Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM).
For research use only. We do not sell to patients.
- CAS No.: 77165-80-1
- Formula: C27H32O8
- Molecular Weight:484.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | ED50 |
≥ 5 μg/mL
Compound: 6
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Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 16792420] |
| KB | ED50 |
≥ 5 μg/mL
Compound: 6
|
Cytotoxicity against human KB cells by MTT assay
Cytotoxicity against human KB cells by MTT assay
|
[PMID: 16792420] |
Chemical Information
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CAS No. 77165-80-1
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Molecular Weight 484.54
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Formula C27H32O8
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SMILES
O=C(/C(C)=C/C)O[C@H]1C2=C(C3=C(C(OC)=C(C=C3C[C@H]([C@H]1C)C)OC)O)C(OC)=C4OCOC4=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)