77165-80-1
77165-80-1
Chemical Structure
Angeloylbinankadsurin A
- CAS No.: 77165-80-1
- Formula:C27H32O8
- Molecular Weight:484.54
InChIKey: CQWHTXPRAFEPNO-QWIXNWPKSA-N
SMILES: O=C(/C(C)=C/C)O[C@H]1C2=C(C3=C(C(OC)=C(C=C3C[C@H]([C@H]1C)C)OC)O)C(OC)=C4OCOC4=C2
Biological Activity: Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM). Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM)[1].
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Angeloylbinankadsurin A | Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM). Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM). | |||||||||||||||||||||
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