1. Metabolic Enzyme/Protease
  2. RAR/RXR
  3. PA452

PA452 

Cat. No.: HY-108522 Purity: >99.0%
Handling Instructions

PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development.

For research use only. We do not sell to patients.

PA452 Chemical Structure

PA452 Chemical Structure

CAS No. : 457657-34-0

Size Price Stock Quantity
1 mg USD 175 In-stock
Estimated Time of Arrival: December 31
5 mg USD 620 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development[1].

IC50 & Target[1]

RXR

 

In Vitro

PA452 inhibits the Troglitazone (TZ)-induced CK13 expression[2].
PA452 (0.01, 0.1, and 1 μM) inhibits RXR in normal human urothelial (NHU) cells[2].

Molecular Weight

439.59

Formula

C₂₆H₃₇N₃O₃

CAS No.

457657-34-0

SMILES

O=C(C1=CN=C(N(C2=C(OCCCCCC)C=C3C(C)(C)CCC(C)(C)C3=C2)C)N=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PA452PA 452PA-452RAR/RXRRetinoic acid receptorsRetinoid X receptorsretinoic XRXRTh1/Th2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
PA452
Cat. No.:
HY-108522
Quantity:
MCE Japan Authorized Agent: