1. Vitamin D Related/Nuclear Receptor
  2. Estrogen Receptor/ERR
  3. ERα degrader 12

ERα degrader 12 (Compound RA3) is an estrogen receptor α (ERα) degrader with antitumor properties. ERα degrader 12 induces pronounced tumor growth inhibition in a breast cancer xenograft mouse model.

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ERα degrader 12

ERα degrader 12 Estructura química

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Descripciòn

ERα degrader 12 (Compound RA3) is an estrogen receptor α (ERα) degrader with antitumor properties. ERα degrader 12 induces pronounced tumor growth inhibition in a breast cancer xenograft mouse model[1].

Peso molecular

699.81

Fòrmula

C39H41NO9S

SMILES

OC1=CC=C(C=C1)C2=C(C(C3=CC=C(OCCCNC([C@@]4(C5[C@@]67C([C@@H](CC5)C)CC[C@@](OO6)(O[C@H]7O4)C)C)=O)C=C3)=O)C8=CC=C(O)C=C8S2

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Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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ERα degrader 12 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
ERα degrader 12
Cat. No.:
HY-170806
Cantidad:
MCE Japan Authorized Agent: