RA190-PEG1-NH2
RA190-PEG1-NH2 (Compound S16) is a derivative of RA190 (HY-100739) and acts as a Proteasome ligand. RA190-PEG1-NH2 can be used for the synthesis of the FKBP12 PROTAC degrader RAFKBP12 (HY-181498).
For research use only. We do not sell to patients.
- CAS No.: 2375455-68-6
- Formula: C32H31Cl4N3O3
- Molecular Weight:647.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Rpn13 |
In Vitro
Proteasome ligands are recruiting ligand components for protein degradation tools such as PROTAC, which can bind to E3 ligase and mediate the ubiquitination and degradation of target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2375455-68-6
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Molecular Weight 647.42
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Formula C32H31Cl4N3O3
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SMILES
NCCOCCN[C@H](C(N1C/C(C(/C(C1)=C/C2=CC(Cl)=C(Cl)C=C2)=O)=C\C3=CC=C(Cl)C(Cl)=C3)=O)CC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RA190-PEG1-NH2 Related Classifications
HY-181499 Related Classifications
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