RA190-PEG1-NH2
RA190-PEG1-NH2 (Compound S16) is a derivative of RA190 (HY-100739) and acts as a Proteasome ligand. RA190-PEG1-NH2 can be used for the synthesis of the FKBP12 PROTAC degrader RAFKBP12 (HY-181498).
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- CAS. Nr.: 2375455-68-6
- Formel: C32H31Cl4N3O3
- Molecular Weight:647.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Rpn13 |
In Vitro
Proteasome ligands are recruiting ligand components for protein degradation tools such as PROTAC, which can bind to E3 ligase and mediate the ubiquitination and degradation of target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2375455-68-6
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Molecular Weight 647.42
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Formel C32H31Cl4N3O3
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SMILES
NCCOCCN[C@H](C(N1C/C(C(/C(C1)=C/C2=CC(Cl)=C(Cl)C=C2)=O)=C\C3=CC=C(Cl)C(Cl)=C3)=O)CC4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RA190-PEG1-NH2 Related Classifications
HY-181499 Related Classifications
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