5,6-Epoxyretinoic acid
all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s=77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 μM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.
For research use only. We do not sell to patients.
- CAS No.: 13100-69-1
- Formula: C20H28O3
- Molecular Weight:316.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Human Endogenous Metabolite |
Chemical Information
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CAS No. 13100-69-1
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Molecular Weight 316.43
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Formula C20H28O3
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SMILES
CC12OC1(C(C)(CCC2)C)/C=C/C(C)=C/C=C/C(C)=C/C(O)=O
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Synonyms
5,6-epoxy atRA; 5,6-epoxy RA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)