5,6-Epoxyretinoic acid

(Synonyms: 5,6-epoxy atRA; 5,6-epoxy RA)

all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s=77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 μM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.

For research use only. We do not sell to patients.

  • CAS No.: 13100-69-1
  • Formula: C20H28O3
  • Molecular Weight:316.43
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All RAR/RXR Isoforms

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