SCHIP1 - schwannomin interacting protein 1 Gene

Also Known as SCHIP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29970

About SCHIP1

Cytogenetic location: 3q25.32-q25.33 Genomic coordinates (GRCh38): 3:159,273,244-159,897,359 (from NCBI)

This gene has 8 transcripts (splice variants) and 282 orthologues. Biased expression in brain (RPKM 38.6), heart (RPKM 21.8) and 13 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in positive regulation of hippo signaling. Predicted to act upstream of or within several processes, including animal organ development; face morphogenesis; and fibroblast migration. Located in several cellular components, including cell junction; cytosol; and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

SCHIP1 Products (31)

mRNA Protein Name
NM_001197107.2 NP_001184036.1 schwannomin-interacting protein 1 isoform 2
NM_001197108.2 NP_001184037.1 schwannomin-interacting protein 1 isoform 3
NM_001197109.2 NP_001184038.1 schwannomin-interacting protein 1 isoform 4
NM_001394282.1 NP_001381211.1 schwannomin-interacting protein 1 isoform 5
NM_001394283.1 NP_001381212.1 schwannomin-interacting protein 1 isoform 5
NM_001394284.1 NP_001381213.1 schwannomin-interacting protein 1 isoform 5
NM_001394285.1 NP_001381214.1 schwannomin-interacting protein 1 isoform 5
NM_001394286.1 NP_001381215.1 schwannomin-interacting protein 1 isoform 5
NM_001394287.1 NP_001381216.1 schwannomin-interacting protein 1 isoform 6
NM_001394288.1 NP_001381217.1 schwannomin-interacting protein 1 isoform 6
NM_001394289.1 NP_001381218.1 schwannomin-interacting protein 1 isoform 6
NM_001394290.1 NP_001381219.1 schwannomin-interacting protein 1 isoform 6
NM_001394291.1 NP_001381220.1 schwannomin-interacting protein 1 isoform 6
NM_001394292.1 NP_001381221.1 schwannomin-interacting protein 1 isoform 7
NM_001394293.1 NP_001381222.1 schwannomin-interacting protein 1 isoform 8
NM_001394294.1 NP_001381223.1 schwannomin-interacting protein 1 isoform 9
NM_001394295.1 NP_001381224.1 schwannomin-interacting protein 1 isoform 10
NM_001394296.1 NP_001381225.1 schwannomin-interacting protein 1 isoform 11
NM_001414415.1 NP_001401344.1 schwannomin-interacting protein 1 isoform 12
NM_001414416.1 NP_001401345.1 schwannomin-interacting protein 1 isoform 13
NM_001414417.1 NP_001401346.1 schwannomin-interacting protein 1 isoform 14
NM_001414418.1 NP_001401347.1 schwannomin-interacting protein 1 isoform 5
NM_001414419.1 NP_001401348.1 schwannomin-interacting protein 1 isoform 5
NM_001414420.1 NP_001401349.1 schwannomin-interacting protein 1 isoform 6
NM_001414421.1 NP_001401350.1 schwannomin-interacting protein 1 isoform 6
NM_001414422.1 NP_001401351.1 schwannomin-interacting protein 1 isoform 6
NM_001414423.1 NP_001401352.1 schwannomin-interacting protein 1 isoform 15
NM_001414424.1 NP_001401353.1 schwannomin-interacting protein 1 isoform 16
NM_001414425.1 NP_001401354.1 schwannomin-interacting protein 1 isoform 17
NM_001414426.1 NP_001401355.1 schwannomin-interacting protein 1 isoform 18
NM_014575.4 NP_055390.1 schwannomin-interacting protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
10669747 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20195357 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

schwannomin-interacting protein 1

SCHIP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SCHIP1 P0DPB3 SCOC Homo sapiens Q9UIL1
Anti Tag CoIP
33961781
Intra
SCHIP1 P0DPB3 PSMD4 Homo sapiens P55036
Display Tech
20195357
Intra
SCHIP1 P0DPB3 SCOC Homo sapiens Q9UIL1
Display Tech
20195357
Intra
SCHIP1 P0DPB3 SCHIP1 Homo sapiens P0DPB3
Pull Down
10669747
Intra
SCHIP1 P0DPB3 SCHIP1 Homo sapiens P0DPB3
Display Tech
20195357
Intra
SCHIP1 P0DPB3 SCOC Homo sapiens Q9UIL1
TAP
20195357
Intra
SCHIP1 P0DPB3 ZC3H13 Homo sapiens Q5T200
Display Tech
20195357
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12510 SCHIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SCHIP1 RGD RGD:1309962
Mus musculus SCHIP1 MGD MGI:1353557