ZC3H13 - zinc finger CCCH-type containing 13 Gene

Also Known as Xio; KIAA0853

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23091

About ZC3H13

Cytogenetic location: 13q14.13 Genomic coordinates (GRCh38): 13:45,954,465-46,052,746 (from NCBI)

This gene has 6 transcripts (splice variants) and 158 orthologues. Ubiquitous expression in brain (RPKM 10.7), thyroid (RPKM 9.2) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mRNA methylation. Located in nuclear speck. Part of RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H13 Products (15)

mRNA Protein Name
NM_001076788.2 NP_001070256.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330564.2 NP_001317493.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330565.2 NP_001317494.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330566.2 NP_001317495.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330567.2 NP_001317496.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382206.1 NP_001369135.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382207.1 NP_001369136.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382208.1 NP_001369137.1 zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382209.1 NP_001369138.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382210.1 NP_001369139.1 zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382211.1 NP_001369140.1 zinc finger CCCH domain-containing protein 13 isoform 4
NM_001382212.1 NP_001369141.1 zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382213.1 NP_001369142.1 zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382214.1 NP_001369143.1 zinc finger CCCH domain-containing protein 13 isoform 6
NM_015070.6 NP_055885.3 zinc finger CCCH domain-containing protein 13 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20195357 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA processing IMP
IMP: Inferred from mutant phenotype
29507755 GOA
Cellular Component GO Annotation Evidence References Source
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: Inferred from direct assay
29507755 GOA
part of RNA N6-methyladenosine methyltransferase complex IPI
IPI: Inferred from physical interaction
29507755 GOA
located in nuclear speck IDA
IDA: Inferred from direct assay
24100041 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
24100041 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H13 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (42 - 63)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1668 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH domain-containing protein 13

ZC3H13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZC3H13 Q5T200 SCHIP1 Homo sapiens P0DPB3
Display Tech
20195357
Cross: Cross-species interaction Intra: Intraspecies interaction

ZC3H13 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810974 ZC3H13 Antibody WB, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Uterine Corpus Endometrial Carcinoma
Wilms Tumor 1

  • Nephroblastoma

  • Wilms Tumor

  • WT1

  • Wilms' Tumor

  • Bilateral Wilms Tumor

  • Wilms Tumor, Type 1

  • Wilms Tumor, Somatic

  • Adult Nephroblastoma

  • Wt1 Disorder

  • Renal Embryonic Tumor

  • Adult Kidney Wilms Tumor

  • Childhood Kidney Wilms Tumor

  • Nonanaplastic Kidney Wilms Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15988 ZC3H13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20618 Zc3h13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27126 Zc3h13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZC3H13 VGNC VGNC:37101
Rattus norvegicus ZC3H13 RGD RGD:1307729
Canis familiaris ZC3H13 VGNC VGNC:48554
Macaca mulatta ZC3H13 VGNC VGNC:79248
Felis catus ZC3H13 VGNC VGNC:67183
Mus musculus ZC3H13 MGD MGI:1914552
Others ZC3H13 NCBI