ZC3H13 Antibody
(Synonyms: KIAA0853, ZC3H13, Zinc finger CCCH domain-containing protein 13)ZC3H13 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to ZC3H13.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
ZC3H13 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to ZC3H13.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 197 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 196 kDa
Synthetic peptide corresponding to the C-term region of human ZC3H13.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
ZC3H13 is an Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR (By similarity). Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (By similarity). In the WMM complex, anchors component of the MACOM subcomplex in the nucleus (By similarity). Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B) (By similarity)[1].
-
Subcellular Localization
Nucleus speckle; Nucleus, nucleoplasm
-
Isoforms & Post-Translational Modification
ZC3H13 has 2 isoforms, Q5T200-1: amino acid length is 1668, molecular weight is 196635 Da (predicted); Q5T200-2: amino acid length is 1564, molecular weight is 184869 Da (predicted).
-
Subunit
Component of the WMM complex, a N6-methyltransferase complex composed of a catalytic subcomplex, named MAC, and of an associated subcomplex, named MACOM.
-
SwissProt ID
-
Synonyms
KIAA0853, ZC3H13, Zinc finger CCCH domain-containing protein 13
Documentation
Powered by Bioz
