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  3. OSTM1 Protein, Mouse (HEK293, His)

OSTM1 Protein is crucial for osteoclast and melanocyte maturation and function, forming heteromers with alpha subunits (CLCN7) to create chloride channel 7. OSTM1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSTM1 protein, expressed by HEK293 , with C-His labeled tag.

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  • Descripciòn

Descripciòn

OSTM1 Protein is crucial for osteoclast and melanocyte maturation and function, forming heteromers with alpha subunits (CLCN7) to create chloride channel 7. OSTM1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSTM1 protein, expressed by HEK293 , with C-His labeled tag.

Background

OSTM1 Protein is essential for the maturation and proper functioning of osteoclasts and melanocytes. It forms heteromers with alpha subunits (CLCN7) to create chloride channel 7.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q8BGT0 (A35-S288)

Gene ID
Molecular Construction
N-term
OSTM1 (A35-S288)
Accession # Q8BGT0
His
C-term
Protein Length

Lumenal Domain

Synonyms
Osteopetrosis-associated transmembrane protein 1; Chloride channel 7 beta subunit; GL
AA Sequence

ALPFTSSRHPGFADLLSEQQLLEVQDLTLSLLQGGGLGPLSLLPPDLPDLEPECRELLMDFANSSAELTACMVRSARPVRLCQTCYPLFQQVAIKMDNISRNIGNTSEGPRCGGSLLTADRMQIVLMVSEFFNSTWQEANCANCLTNNGEDLSNNTEDFLSLFNKTLACFEHNLQGHTYSLLPPKNYSEVCRNCKEAYKNLSLLYSQMQKLNGLENKAEPETHLCIDVEDAMNITRKLWSRTFNCSVTCSDTVS

Peso molecular

Approximately 30-60 kDa due to the glycosylation

Glycosylation
Yes
Pureza
  • ≥ 95%, as determined by reducing SDS-PAGE.
Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Envío

Room temperature in continental US; may vary elsewhere.

Documentación

OSTM1 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Inquiry Information

Nombre del producto:
OSTM1 Protein, Mouse (HEK293, His)
Cat. No.:
HY-P77117
Cantidad:
MCE Japan Authorized Agent: