p73 beta Protein, Human (sf9, GST)
p73 beta Protein, Human (sf9, GST) is the recombinant human-derived p73 beta, expressed by Sf9 insect cells , with GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
p73 beta Protein, Human (sf9, GST) is the recombinant human-derived p73 beta, expressed by Sf9 insect cells , with GST labeled tag. ,
Background
p73 alpha is a protein involved in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, while those lacking this domain are anti-apoptotic and inhibit the function of p53 and transactivating p73 isoforms. It may act as a tumor suppressor protein. Additionally, p73 alpha is an activator of FOXJ1 expression (by similar) and serves as an essential factor for the positive regulation of lung ciliated cell differentiation.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
O15350-2 (M1-P499)
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Gene ID7161
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Protein Length
Full Length of Isoform-2
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Synonyms
TP73; Transcription Factor DNp73; Tumor Protein P73; Cellular Tumor Antigen P53; P73; DeltaN P73; P53-Like Transcription Factor; CILD47; P53-Related Protein; HDNp73
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AA Sequence
MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
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Molecular Weight
Approximately 88 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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