PGM2 Protein, Human (His)
Based on 1 Customer Validation
PGM2 Protein is a protein of the alpha-d-phosphohexomutase family. PGM2 has phosphopentomutase activity, that is involved in carbohydrate metabolic process and deoxyribose phosphate catabolic process. The high expression of PGM2 can improve the overall survival rate of patients and have an inhibitory effect on tumors. PGM2 Protein, Human (His) is the recombinant human-derived PGM2 protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
PGM2 Protein is a protein of the alpha-d-phosphohexomutase family. PGM2 has phosphopentomutase activity, that is involved in carbohydrate metabolic process and deoxyribose phosphate catabolic process. The high expression of PGM2 can improve the overall survival rate of patients and have an inhibitory effect on tumors. PGM2 Protein, Human (His) is the recombinant human-derived PGM2 protein, expressed by E. coli , with N-6*His labeled tag.
Phosphopentomutase 2 (PGM2) is a protein of the alpha-d-phosphohexomutase family. PGM2 has phosphopentomutase activity, that is involved in carbohydrate metabolic process and deoxyribose phosphate catabolic process. PGM2 catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses, catalyzes the interconversion of glucose-1-phosphate into glucose-6-phosphate but with a lower catalytic efficiency. It has also a low glucose 1,6-bisphosphate synthase activity. The high expression of PGM2 can improve the overall survival rate of patients and have an inhibitory effect on tumors[1][2][3].
The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
AAH10087.1 (M1-D612)
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Molecular Construction
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N-term
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6*His
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PGM2 (M1-D612)
Accession # AAH10087.1 -
C-term
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Protein Length
Full Length
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Synonyms
PGM2; FLJ10983; Phosphoglucomutase 2; Phosphoglucomutase-2; Phosphopentomutase; MSTP006; Glucose Phosphomutase 2; PGM 2; Phosphodeoxyribomutase
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AA Sequence
MAAPEGSGLDEDARLDQETAQWLRWDKNSLTLEAVKRLIAEGNKEELRKCFGARMEFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRFARLAATTFISQGIPVYLFSDITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINNDYFEDLKKYCFHRSVNRETKVKFVHTSVHGVGHSFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHITKASYFICHDQETIKKLFENLRNYDGKNNYPKACGKFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD
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Predicted Molecular Mass
70.5 kDa
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Molecular Weight
Approximately 65-75 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 0.06% Tween 80, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
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Data Sheet (239 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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