PLXDC2 Protein, Human (HEK293, His)

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Based on 1 Customer Validation

PLXDC2 protein potentially contributes to tumor angiogenesis, influencing blood vessel formation in tumors. It interacts with CTTN, suggesting involvement in cellular activities related to cytoskeletal dynamics and cell migration. PLXDC2 Protein, Human (HEK293, His) is the recombinant human-derived PLXDC2 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

PLXDC2 protein potentially contributes to tumor angiogenesis, influencing blood vessel formation in tumors. It interacts with CTTN, suggesting involvement in cellular activities related to cytoskeletal dynamics and cell migration. PLXDC2 Protein, Human (HEK293, His) is the recombinant human-derived PLXDC2 protein, expressed by HEK293 , with C-His labeled tag.

Background

PLXDC2 protein may play a significant role in tumor angiogenesis, potentially influencing the process of blood vessel formation within tumor tissues. Additionally, it interacts with CTTN, suggesting a possible involvement in cellular activities associated with cytoskeletal dynamics and cell migration.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-8*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • PLXDC2 (K31-A454)
      Accession # Q6UX71-1
    • 8*His
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    PLXDC2; Plexin Domain-Containing Protein 2; Plexin Domain Containing 2; FLJ14623; TEM7R; Tumor Endothelial Marker 7-Related Precursor; PLXDC2-OT; 1200007L24Rik; Tumor Endothelial Marker 7-Related Protein

  • AA Sequence

    KPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPRSFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKMCENTEPVETSSRTTTTVGATTTQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHA

  • Predicted Molecular Mass

    49.1 kDa

  • Molecular Weight

    Approximately 75-95 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Endotoxin Level

<0.05 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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