Semaphorin-3A/SEMA3A Protein, Rat (His)
Based on 1 publication(s) in Google Scholar
Semaphorin-3A/SEMA3A protein plays a potentially crucial role in directing axon growth by creating molecular boundaries that guide the formation of specific nerve tracts. Its binding to neuropilin is implicated in olfactory system development and neuronal regulation of puberty. SEMA3A's interaction with PLXND1 underscores its significance in axon guidance and neural development. Semaphorin-3A/SEMA3A Protein, Rat (His) is the recombinant rat-derived Semaphorin-3A/SEMA3A protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Rat
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Semaphorin-3A/SEMA3A protein plays a potentially crucial role in directing axon growth by creating molecular boundaries that guide the formation of specific nerve tracts. Its binding to neuropilin is implicated in olfactory system development and neuronal regulation of puberty. SEMA3A's interaction with PLXND1 underscores its significance in axon guidance and neural development. Semaphorin-3A/SEMA3A Protein, Rat (His) is the recombinant rat-derived Semaphorin-3A/SEMA3A protein, expressed by E. coli , with N-6*His labeled tag.
Background
Semaphorin-3A/SEMA3A protein is potentially crucial for directing the growth of axons towards their intended targets by creating a molecular boundary that provides instructions for the formation of specific nerve tracts. It binds to neuropilin and is implicated in the development of the olfactory system and the neuronal regulation of puberty. Additionally, SEMA3A interacts with PLXND1, further emphasizing its significance in axon guidance and neural development.
Publications (1)
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Journal Impact Factor
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Most Recent
Technical Parameters
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Species Rat
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Source E. coli
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Tag N-6*His
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Accession
Q63548 (N21-V772)
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Molecular Construction
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N-term
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6*His
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SEMA3A (N21-V772)
Accession # Q63548 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
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AA Sequence
NYANGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFNLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEVGHHPEDNIFKLQDSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPRFISAHLIPESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNSKDPKNPIVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPINNRPIMIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSVPKETWHDLEEVLLEEMTVFREPTTISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSSCSRYFPTAKRRTRRQDIRNGDPLTHCSDLQHHDNHHGHSLEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEDRKEEIRVGDHIIRTEQGLLLRSLQKKDSGNYLCHAVEHGFMQTLLKVTLEVIDTEHLEELLHKDDDGDGSKTKEMSSSMTPSQKVWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPGHSQGSSNKWKHMQESKKGRNRRTHEFERAPRSV
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Predicted Molecular Mass
90.6 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder
Lyophilized from a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4 or10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (239 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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