Sema3a - semaphorin 3A Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29751

Summary

Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Involved in apoptotic process and negative regulation of axon extension. Acts upstream of or within axon guidance. Located in axon and dendrite. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia. Orthologous to human SEMA3A (semaphorin 3A). [provided by Alliance of Genome Resources, Apr 2022]

Sema3a Products (1)

mRNA Protein Name
NM_017310.2 NP_059006.1 semaphorin-3A precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IGI
IGI: Inferred from genetic interaction
21068336 RGD
involved in negative regulation of axon extension IDA
IDA: Inferred from direct assay
12077190 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
15866045 RGD
located in dendrite IDA
IDA: Inferred from direct assay
15866045 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

semaphorin-3A

  • sema III

  • sema domain, immunoglobulin domain (Ig), short basic domain, sec

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

  • semaphorin III

Recombinant Sema3a Proteins

Cat. No. Product Name Accession Purity
HY-P71564 Semaphorin-3A/SEMA3A Protein, Rat (His) Q63548 (N21-V772) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103511 TCS1105 99.44% Unkown
HY-RS12650 SEMA3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17258 Sema3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23712 Sema3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992302 Anti-SEMA3A Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sema3a NCBI NCBI:10371