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SLITRK4 Protein, Human (HEK293, His)

Cat. No.: HY-P77207
Handling Instructions

SLITRK4 Protein is pivotal in synaptogenesis, promoting synapse differentiation and synaptic maturation. Conversely, it suppresses neurite outgrowth, indicating a regulatory role in neuronal morphology. Interacting with PTPRD through its LRR 1 and 2 repeats, SLITRK4 suggests a potential role in modulating the activity or function of PTPRD, a receptor-type protein tyrosine phosphatase associated with neural development and synaptic plasticity. SLITRK4 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK4 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLITRK4 Protein, Human (HEK293, His) is 598 a.a., with molecular weight of ~85 kDa.

For research use only. We do not sell to patients.

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Description

SLITRK4 Protein is pivotal in synaptogenesis, promoting synapse differentiation and synaptic maturation. Conversely, it suppresses neurite outgrowth, indicating a regulatory role in neuronal morphology. Interacting with PTPRD through its LRR 1 and 2 repeats, SLITRK4 suggests a potential role in modulating the activity or function of PTPRD, a receptor-type protein tyrosine phosphatase associated with neural development and synaptic plasticity. SLITRK4 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK4 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLITRK4 Protein, Human (HEK293, His) is 598 a.a., with molecular weight of ~85 kDa.

Background

SLITRK4 plays a crucial role in synaptogenesis, actively promoting the differentiation of synapses, as evidenced by its involvement in synaptic maturation. Conversely, SLITRK4 suppresses neurite outgrowth, indicating a regulatory function in neuronal morphology. The protein interacts with PTPRD through its LRR 1 and 2 repeats, suggesting a potential role in modulating the activity or function of PTPRD, a receptor-type protein tyrosine phosphatase known for its involvement in neural development and synaptic plasticity.

Species

Human

Source

HEK293

Tag

C-His

Accession

Q8IW52 (D19-P616)

Gene ID
Molecular Construction
N-term
SLITRK4 (D19-P616)
Accession # Q8IW52
His
C-term
Synonyms
SLIT and NTRK-like protein 4; SLITRK4
Molecular Weight

Approximately 85 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SLITRK4 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLITRK4 Protein, Human (HEK293, His)
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HY-P77207
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