TRF1 Protein, Human (sf9, His)
CHST1 protein is a protein involved in the sulfation process of glycosaminoglycans. It plays a crucial role in regulating cellular functions such as cell adhesion and signaling. TRF1 Protein, Human (sf9, His) is the recombinant human-derived TRF1 protein, expressed by Sf9 insect cells , with N-His labeled tag.
- Species: Human
- Source: Sf9 insect cells
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
CHST1 protein is a protein involved in the sulfation process of glycosaminoglycans. It plays a crucial role in regulating cellular functions such as cell adhesion and signaling. TRF1 Protein, Human (sf9, His) is the recombinant human-derived TRF1 protein, expressed by Sf9 insect cells , with N-His labeled tag.
Background
The TRF1 Protein is encoded by this gene and serves as a telomere-specific component within the telomere nucleoprotein complex. Maintained at telomeres throughout the cell cycle, TRF1 acts as an inhibitor of telomerase, playing a crucial role in limiting the elongation of individual chromosome ends. The protein structure features a C-terminal Myb motif, a dimerization domain near its N-terminus, and an acidic N-terminus. Multiple transcripts of this gene result from alternative splicing. TRF1 displays ubiquitous expression, with notable levels detected in the brain (RPKM 11.2), ovary (RPKM 9.8), and 25 other tissues. This broad expression pattern underscores its essential role in various physiological contexts across multiple organs.
Technical Parameters
-
Species Human
-
Source Sf9 insect cells
-
Tag N-His
-
Accession
P54274-2/NP_003209 (M1-D419)
-
Molecular Construction
-
N-term
-
His
-
TRF1 (M1-D419)
Accession # NP_003209 -
C-term
-
-
Protein Length
Full Length of Isoform-2
-
Synonyms
TERF1; Telomeric Repeat-Binding Factor 1; Prev. TRBF1; Telomeric Protein Pin2/TRF1; PIN2; NIMA-Interacting Protein 2; TRF1; Telomeric Repeat-Binding Factor; TRF; HTRF1-AS; Telomeric Repeat Binding Factor (NIMA-Interacting) 1; T-TRF1; Telomeric Repeat Bind
-
AA Sequence
MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
-
Predicted Molecular Mass
50.5 kDa
-
Molecular Weight
Approximately 60 kDa, based on SDS-PAGE under reducing conditions.
-
Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
