RIP1 Kinase inhibitor 1 (Standard)
RIP1 Kinase inhibitor 1 (Standard) is the analytical standard of RIP1 Kinase inhibitor 1 (HY-111409). This product is intended for research and analytical applications. RIP1 Kinase inhibitor 1 (compound 22) is a highly potent, orally available, and brain-penetrating RIP1 Kinase inhibitor (pKi=9.04).
For research use only. We do not sell to patients.
- CAS No.: 2095515-38-9
- Formula: C24H20ClN5O3
- Molecular Weight:461.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2095515-38-9
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Molecular Weight 461.90
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Formula C24H20ClN5O3
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SMILES
N#CC1=CC=C2N(C)C([C@@H](N3CCC4=C(Cl)N(CC5=CC=CC=C5)N=C4C3=O)COC2=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yoshikawa M, et al. Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, OrallyAvailable, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships. J Med Chem. 2018 Mar 22;61(6):2384-2409. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RIP1 Kinase inhibitor 1 (Standard) Related Classifications
HY-111409R Related Classifications
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