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Cat. No.: HY-101336R

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RS 17053 hydrochloride (Standard)

Name: RS 17053 hydrochloride (Standard)
Brand: MedChemExpress
SKU: HY-101336R
Price: 90.00 USD
Availability: InStock
Rating: 5 (1 reviews)

RS 17053 (hydrochloride) (Standard) is the analytical standard of RS 17053 (hydrochloride) (HY-101336). This product is intended for research and analytical applications. RS 17053 (hydrochloride) is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 169505-93-5
Formula: C₂₄H₃₀Cl₂N₂O₂
Molecular Weight:449.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

RS 17053 hydrochloride (Standard) Chemical Structure

CAS No.: 169505-93-5

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 169505-93-5
Molecular Weight 449.41
Formula C₂₄H₃₀Cl₂N₂O₂
SMILES

ClC1=CC2=C(NC=C2CC(C)(C)NCCOC3=CC=CC=C3OCC4CC4)C=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Ford AP, et al. RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification. Mol Pharmacol. 1996 Feb;49(2):209-15. [Content Brief]

[2]. Wellman PJ, et al. Effects of the alpha 1a-adrenoceptor antagonist RS-17053 on phenylpropanolamine-induced anorexia in rats. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):281-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RS 17053 hydrochloride (Standard)