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  3. Drug Intermediate
  4. (S,S,S,S,R)-Boc-Dap-NE

(S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

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(S,S,S,S,R)-Boc-Dap-NE

(S,S,S,S,R)-Boc-Dap-NE 화학구조

CAS No. : 3026594-75-9

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of (S,S,S,S,R)-Boc-Dap-NE:

(S,S,S,S,R)-Boc-Dap-NE Related Antibodies

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제품 설명

(S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

분자량

420.54

화학식

C23H36N2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1[C@@H](CCC1)[C@H]([C@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)OC(C)(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도
In Vitro: 

DMSO : 200 mg/mL (475.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3779 mL 11.8895 mL 23.7789 mL
5 mM 0.4756 mL 2.3779 mL 4.7558 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
순도&문서

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3779 mL 11.8895 mL 23.7790 mL 59.4474 mL
5 mM 0.4756 mL 2.3779 mL 4.7558 mL 11.8895 mL
10 mM 0.2378 mL 1.1889 mL 2.3779 mL 5.9447 mL
15 mM 0.1585 mL 0.7926 mL 1.5853 mL 3.9632 mL
20 mM 0.1189 mL 0.5945 mL 1.1889 mL 2.9724 mL
25 mM 0.0951 mL 0.4756 mL 0.9512 mL 2.3779 mL
30 mM 0.0793 mL 0.3963 mL 0.7926 mL 1.9816 mL
40 mM 0.0594 mL 0.2972 mL 0.5945 mL 1.4862 mL
50 mM 0.0476 mL 0.2378 mL 0.4756 mL 1.1889 mL
60 mM 0.0396 mL 0.1982 mL 0.3963 mL 0.9908 mL
80 mM 0.0297 mL 0.1486 mL 0.2972 mL 0.7431 mL
100 mM 0.0238 mL 0.1189 mL 0.2378 mL 0.5945 mL
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(S,S,S,S,R)-Boc-Dap-NE Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,S,S,S,R)-Boc-Dap-NE3026594-75-9Drug IntermediateDrug IintermediateInhibitorinhibitorinhibit

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상품명:
(S,S,S,S,R)-Boc-Dap-NE
Cat. No.:
HY-78931B
수량:
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