(S,S,S,S,R)-Boc-Dap-NE
Based on 1 Customer Validation
(S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 3026594-75-9
- Formula: C23H36N2O5
- Molecular Weight:420.54
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Chemical Information
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CAS No. 3026594-75-9
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Appearance Solid
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Molecular Weight 420.54
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Formula C23H36N2O5
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Color White to off-white
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SMILES
O=C(N1[C@@H](CCC1)[C@H]([C@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)OC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 200 mg/mL (475.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3779 mL | 11.8895 mL | 23.7790 mL | 59.4474 mL |
| 5 mM | 0.4756 mL | 2.3779 mL | 4.7558 mL | 11.8895 mL | |
| 10 mM | 0.2378 mL | 1.1889 mL | 2.3779 mL | 5.9447 mL | |
| 15 mM | 0.1585 mL | 0.7926 mL | 1.5853 mL | 3.9632 mL | |
| 20 mM | 0.1189 mL | 0.5945 mL | 1.1889 mL | 2.9724 mL | |
| 25 mM | 0.0951 mL | 0.4756 mL | 0.9512 mL | 2.3779 mL | |
| 30 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.9816 mL | |
| 40 mM | 0.0594 mL | 0.2972 mL | 0.5945 mL | 1.4862 mL | |
| 50 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1889 mL | |
| 60 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9908 mL | |
| 80 mM | 0.0297 mL | 0.1486 mL | 0.2972 mL | 0.7431 mL | |
| 100 mM | 0.0238 mL | 0.1189 mL | 0.2378 mL | 0.5945 mL |