SARS-CoV-2 Mpro-IN-48
SARS-CoV-2 Mpro-IN-48 is a potent SARS-CoV-2 main protease inhibitor with an IC50 of 21.1 nM. SARS-CoV-2 Mpro-IN-48 exhibits potent antiviral activity against the SARS-CoV-2 JN.1 variant. SARS-CoV-2 Mpro-IN-48 can be used for the research of infection, such as COVID-19.
For research use only. We do not sell to patients.
- Formula: C22H14ClF2N3O2
- Molecular Weight:425.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
SARS-CoV-2 |
In Vitro
SARS-CoV-2 Mpro-IN-48 shows low cytotoxicity to Vero E6 cells with a CC50 of 33.26 μM[1].
SARS-CoV-2 Mpro-IN-48 exhibits potent antiviral activity against the SARS-CoV-2 JN.1 variant in Vero E6 cells with an EC50 <0.002 μM, and its SI reaches 16630[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 425.82
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Formula C22H14ClF2N3O2
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SMILES
O=C1N(C2=CC(C)=CN=C2)C(C(C3=CC=C(F)C(Cl)=C3)=C(C4=CC=C(F)C=C4)N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV-2 Mpro-IN-48 Related Classifications
HY-178435 Related Classifications
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