SARS-CoV-2 Mpro-IN-60
SARS-CoV-2 Mpro-IN-60 is a SARS-CoV-2 Mpro inhibitor with an IC50 of 0.031 μM. SARS-CoV-2 Mpro-IN-60 is applicable to the research of COVID-19.
For research use only. We do not sell to patients.
- Formula: C21H18N4O3S2
- Molecular Weight:438.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
SARS-CoV-2 Mpro-IN-60 (Compound 12c) (0.005-50 μM; 1 h) potently inhibits MBP-tagged SARS-CoV-2 Mpro protein, with an IC50 value of 0.031 μM, which is more potent than Nirmatrelvir (HY-138687)[1].
SARS-CoV-2 Mpro-IN-60 (48 h) exhibits low cytotoxicity in Vero-E6 cells, with a CC50 >100 μM, resulting in a selectivity index of >1708[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 438.52
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Formula C21H18N4O3S2
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SMILES
O=C(NC1=NN=C(SCC(C2=CC=C(O)C(C)=C2)=O)S1)CC3=CNC4=C3C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV-2 Mpro-IN-60 Related Classifications
HY-184733 Related Classifications
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