25 Results for "

Matriptase

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Matriptase" in MCE Product Catalog:

Cat. No.: HY-P992451
Synonyms: KY1066
RLYB331 (KY1066) is a is a monoclonal antibody targeting Matriptase-2 (TMPRSS6) . RLYB331 binds to the serine protease active site of matriptase-2, blocking protease activity to increase hepcidin expression. RLYB331 reduces iron overload, inhibits α-aggregates, reduces ROS, inhibits apoptosis, and enhances erythroid differentiation. RLYB331 ameliorates ineffective erythropoiesis in β-thalassemic mouse models. RLYB331 can be used for the research of β-thalassemia .
loading...
    loading...
Cat. No.: HY-P89613
Synonyms: UNQ354/PRO618, TMPRSS6, Transmembrane protease serine 6, Matriptase-2

Host:  

Mouse

Application:  

WB, ICC/IF, IF-Tissue, IP, ELISA

Reactivity:  

human

loading...
    loading...
Cat. No.: HY-P811026
Synonyms: PRSS14, SNC19, TADG15, ST14, Suppressor of tumorigenicity 14 protein, Matriptase, Membrane-type serine protease 1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, MT-SP1

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-180217
Target:  

TMPRSS6 Factor Xa

Research Areas:  

Cardiovascular Disease

WGU55 is a selective and potent reversible type II transmembrane serine protease TMPRSS6 inhibitor with a Ki of 12.15 nM. WGU55 inhibits TMPRSS6 activity with an IC50 of 138 nMin KEK293 cells. WGU55 has a Ki of 3510 nM (SI = 289) against the homologous protease matriptase and a Ki of 5.2 μM against the coagulation key protease Factor Xa. WGU55 can be used for the research of iron overload related diseases, such as hereditary hemochromatosis .
loading...
    loading...
Cat. No.: HY-179708
CAS No.: 3086979-57-6
Research Areas:  

Infection

Cbz-QFR-kbt is a ketone-based benzothiazole ketone inhibitor of TMPRSS2, with an IC50 value of 0.42 nM. Cbz-QFR-kbt also has inhibitory activity against Matriptase, Hepsin, HGFA, and Factor Xa, with IC50 values of 1, 1.3, 85, and 85 nM respectively. Cbz-QFR-kbt shows significant inhibitory effects against SARS-CoV-2 and H1N1 (IC50 = 60 nM). Cbz-QFR-kbt can be used in antiviral research .
loading...
    loading...