![3-[2-Oxo-6-(4-Pip)-Bz[cd]indol-1-yl]-Pip-2,6-dione](https://file.medchemexpress.com/product_pic/hy-w733139.gif "Click to View 3-[2-Oxo-6-(4-Pip)-Bz[cd]indol-1-yl]-Pip-2,6-dione Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
PIP2
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "PIP2" in MCE Product Catalog:
Cat. No.: HY-W403046A
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D-myo-Inositol-4-phosphate monoammonium is a metabolite of D-myo-Inositol 1,4,5-trisphosphate. D-myo-Inositol 1,4,5-trisphosphate, a second messenger, elicits Ca 2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2) [2] .
Cat. No.: HY-163735
CAS No.: 609335-29-7
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BA6b9 is an allosteric inhibitor of SK4 channels that targets the CaM–PIP2-binding domain with a IC50 value of 8.6 µM (WT SK4). BA6b9 inhibits SK4 channels by interacting with two specific residues, Arg191 and His192 in the S4–S5 linker. BA6b9 significantly prolongs atrial and atrioventricular effective refractory period (ERP) and reduces atrial fibrillation (AF) induction in rat isolated hearts, which has the potential to be used for the research of arrhythmia .
Cat. No.: HY-159617
CAS No.: 3035215-25-6
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Cbz-Pip-2C-Pip-C-Pip is a PROTAC linker. Cbz-Pip-2C-Pip-C-Pip can be used for synthesis PROTAC Cbl-b-IN-1 (HY-159608) .
Cat. No.: HY-157685
CAS No.: 799268-61-4
Synonyms: PIP2[3',5'](6:0/6:0) ammonium
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06:0 PI(3,5)P2 (PIP2[3',5'](6:0/6:0)) ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
Cat. No.: HY-D3302
Synonyms: DOPI-4,5-P2-biotin sodium; Phosphatidylinositol-4,5-diphosphate C-8-biotin sodium; PI(4,5)P2-biotin sodium
Cat. No.: HY-101562R
CAS No.: 2060571-02-8
Synonyms: GDC-0077 (Standard); RG6114 (Standard)
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Inavolisib (Standard) is the analytical standard of Inavolisib (HY-101562). This product is intended for research and analytical applications. Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor (IC50=0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib can be used for the study of breast cancer .
Cat. No.: HY-179554
Synonyms: PI(4,5)P2-fluorescein triethylammonium
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PtdIns-(4,5)-P2-fluorescein (PI(4,5)P2-fluorescein) triethylammonium is a fluorescently labeled phosphatidylinositol-4,5-bisphosphate, which is a marked form of an important phospholipid signaling molecule (PIP2) on the cell membrane. PtdIns-(4,5)-P2-fluorescein triethylammonium can be used to detect proteins that interact with phosphatidylinositol-4,5-bisphosphate, such as PI3K, PTEN, and PH domain proteins, etc .
Cat. No.: HY-32207S
CAS No.: 2089333-15-1
Cat. No.: HY-W010178R
CAS No.: 54947-74-9
Category:
Cat. No.: HY-159618
Research Areas:
(3S)Lenalidomide-5-Pip-C-Pip-2C-Pip is an E3 Ligase Ligand-Linker Conjugate. (3S)Lenalidomide-5-Pip-C-Pip-2C-Pip can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608) .
Cat. No.: HY-15244G
CAS No.: 1217486-61-7
Cat. No.: HY-W733139
CAS No.: 2655646-64-1
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3-[2-Oxo-6-(4-Pip)-Bz[cd]indol-1-yl]-Pip-2,6-dione is a CRBN ligand, which can be used for the synthesis of PROTACs, such as PROTAC PTPN2 degrader-2 (HY-153938) .
Cat. No.: HY-W879795
CAS No.: 1504209-32-8
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NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip) is a CRBN ligand. NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip) can be used to synthesize PROTAC BRD4 Degrader-22 (HY-155393) .
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D-myo-Inositol, 1-[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate] 3,5-bis(dihydrogen phosphate), ammonium salt (1:3)
Cat. No.: HY-157705
CAS No.: 799268-55-6
Synonyms: PIP2[3',5'](18:1(9Z)/18:1(9Z)) triammonium
Cat. No.: HY-110150R
CAS No.: 1031602-63-7
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UNC3230 (Standard) is the analytical standard of UNC3230 (HY-110150). This product is intended for research and analytical applications. UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid Kinases that regulate phosphoinositide levels. UNC3230 has antinociceptive and anticancer effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
