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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
220 Results for "
complementation
" in MedChemExpress (MCE) Product Catalog:
Products (220)
220 Results for "complementation" in MCE Product Catalog:
Synonyms: N-Acetyl-L-serine
Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103
Target:
연구분야:
Target:
연구분야:
FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 µM, respectively .
Cat. No.: HY-P99050
CAS No.: 2049079-64-1
Synonyms: BIVV009; IPN-009; TNT009
Target:
연구분야:
Cat. No.: HY-P99520
CAS No.: 2250440-41-4
Synonyms: CaCP-29, IFX-1
Target:
Cat. No.: HY-P99365
CAS No.: 1803171-55-2
Synonyms: ALXN1210
Target:
연구분야:
Cat. No.: HY-P990952
CAS No.: 2527079-60-1
Synonyms: OMS906
Cat. No.: HY-NP0194A
and non-immune cells. C1q Protein (mouse) can be used for the research of mutiple disease .
Cat. No.: HY-P99358
CAS No.: 1662664-56-3
Synonyms: GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)
Target:
연구분야:
Cat. No.: HY-145720
CAS No.: 1639264-46-2
Synonyms: ALN-CC5
연구분야:
Cemdisiran (ALN-CC5) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR 445088
Cat. No.: HY-148457
CAS No.: 1613641-69-2
Synonyms: Izervay
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
Cat. No.: HY-P99450
CAS No.: 2226393-85-5
Synonyms: IPH 5401; Anti-C5aR1 mAb
Target:
Cat. No.: HY-P99638
CAS No.: 2456407-94-4
Synonyms: ALXN-1720
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연구분야:
Cat. No.: HY-P990025
CAS No.: 2579031-19-7
Synonyms: ARGX-117
Target:
연구분야:
Cat. No.: HY-P1823
CAS No.: 147516-85-6
Cat. No.: HY-P99786
CAS No.: 2096328-94-6
Synonyms: REGN3918
Target:
연구분야:
Synonyms: IONIS-FB-LRx sodium; RG6299 sodium; ISIS 696844 sodium
Target:
연구분야:
Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research .
Cat. No.: HY-148370
CAS No.: 2272975-74-1
Synonyms: IONIS-FB-LRx; RG6299; ISIS 696844
Target:
연구분야:
Sefaxersen (IONIS-FB-LRx) is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen effectively reduces circulating levels of CFB. Sefaxersen can be used for geographic atrophy (GA) research .
Cat. No.: HY-P99298
CAS No.: 1278466-20-8
Synonyms: RG 7417; TNX 234; Anti-CFD Recombinant Antibody
Target:
연구분야:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
