1662664-56-3
Chemical Structure
Dezamizumab
Synonym(s): GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)
- CAS No.: 1662664-56-3
- Formula:N/A
- Molecular Weight:(144.18 kDa)
IUPAC Name: nonyl 4-hydroxybenzoate-2,3,5,6-d4
SMILES: [Dezamizumab]
Biological Activity: Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis[1].
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Dezamizumab | 99.79% | Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis. | ||||||||||||||||||||
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Keywords
