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Avdoralimab

(Synonyms: IPH 5401; Anti-C5aR1 mAb)
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Based on 1 Customer Validation

Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research.

For research use only. We do not sell to patients.

  • Purity: 99.25%
  • CAS No.: 2226393-85-5
  • Molecular Weight:145.9 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Avdoralimab
  • Experimental Validation Results for Avdoralimab
  • Experimental Validation Results for Avdoralimab
  • Avdoralimab Chemical Structure
    Avdoralimab Chemical Structure
CAS No.: 2226393-85-5
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Avdoralimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized C5AR1 Protein-VLP, Human can bind Avdoralimab. The EC50 for this effect is 8.481 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells with Avdoralimab (HY-P99450, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Avdoralimab Chemical Structure
    1/16
  • Avdoralimab
  • Immobilized C5AR1 Protein-VLP, Human can bind Avdoralimab. The EC50 for this effect is 8.481 ng/mL.
  • Flow cytometric analysis of 1X106 HepG2 cells with Avdoralimab (HY-P99450, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).