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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
220 Results for "
complementation
" in MedChemExpress (MCE) Product Catalog:
Products (220)
220 Results for "complementation" in MCE Product Catalog:
Art. -Nr.: HY-163378
CAS. Nr.: 2365325-67-1
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C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 (C5aR1) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases .
Art. -Nr.: HY-N17326
CAS. Nr.: 242794-72-5
Art. -Nr.: HY-P991229
Synonyms: AGS-1C4D4; AGS-PSCA
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Art. -Nr.: HY-N0899
CAS. Nr.: 11088-09-8
Art. -Nr.: HY-P992004
Synonyms: RA15-7, HuRA15-7Acc
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Art. -Nr.: HY-P992034
Synonyms: PR001
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Art. -Nr.: HY-P9961
CAS. Nr.: 679818-59-8
Synonyms: GSK1841157; OMB-157
Art. -Nr.: HY-P990076
CAS. Nr.: 2131168-99-3
Synonyms: APN-301; hu14.18-IL2; EMD 273063
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Art. -Nr.: HY-P992361
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Art. -Nr.: HY-116282A
CAS. Nr.: 9011-18-1
Synonyms: DSS (MW 4500-5500); DXS (MW 4500-5500)
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Dextran sulfate sodium salt (DSS) (MW 4500-5500) is a polymer of dehydrated glucose with a molecular weight of approximately 4500-5500. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 4500-5500) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 4500-5500) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (MW 4500-5500) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
Art. -Nr.: HY-P990941
CAS. Nr.: 2853518-94-0
Synonyms: F131; GEN1184 antibody
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Art. -Nr.: HY-185926
CAS. Nr.: 2364414-05-9
Synonyms: NOX-D21; AON-D21
Forschungsgebiete:
Ldalaptican pegol (AON-D21; NOX-D21) is a PEGylated mixed RNA/DNA L-aptamer that specifically binds to complement C5a. Ldalaptican pegol binds to C5a and the C5a moiety on uncleaved C5, thereby blocking C5a signaling. This inhibition suppresses downstream inflammatory responses, immune cell infiltration and chemotaxis, the release of pro-fibrotic factors, and abnormalities in lipid metabolism signaling pathways. Ldalaptican pegol can also alleviate allograft rejection. Ldalaptican pegol can be used in research on inflammatory muscle diseases, Duchenne muscular dystrophy (DMD), diabetes, renal fibrosis, and allograft organ transplant rejection .
Art. -Nr.: HY-P11137
CAS. Nr.: 878495-58-0
Art. -Nr.: HY-P992291
Art. -Nr.: HY-181040
CAS. Nr.: 3049710-19-9
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Factor B-IN-8 (Compound (3R ,4R )-15) is a potent, selective and orally active factor B inhibitor with an IC50 of 10.2 nM. Factor B-IN-8 can effectively inhibit the binding of factor B to C3b and the subsequent formation of C3 convertase (C3bBb). Factor B-IN-8 can inhibit the deposition of membrane attack complex (MAC) mediated by alternativepathway with an IC50 of 59.3 nM. Factor B-IN-8 can reduce the cleavage of factor B protein and decrease the deposition of complement C3d in the glomeruli and renal tubules. Factor B-IN-8 can be used for researches of arthritis and paroxysmal nocturnal hemoglobinuria (PNH) .
Art. -Nr.: HY-46846
CAS. Nr.: 69011-20-7
Forschungsgebiete:
Styrene-divinylbenzene sulfonated copolymer is a cation exchange resin prepared from sulfonic acid group-containing microporous styrene/divinylbenzene (DVB) copolymer. Styrene-divinylbenzene sulfonated copolymer serves as the core matrix material for most bilirubin adsorbents. It also acts as a hydrophilic cell immobilization carrier, whose porous structure provides an ideal environment for microbial growth and biochemical reactions .
Art. -Nr.: HY-P991425
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Art. -Nr.: HY-P992482
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Art. -Nr.: HY-P99757
CAS. Nr.: 2278244-14-5
Synonyms: Hu3F8-BsAb
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
