131-49-7
Chemical Structure
Diatrizoate meglumine
Synonym(s): Diatrizoic acid meglumine; Amidotrizoic acid meglumine
- CAS No.: 131-49-7
- Formula:C18H26I3N3O9
- Molecular Weight:809.13
IUPAC Name: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3,5-diacetamido-2,4,6-triiodobenzoate
InChIKey: MIKKOBKEXMRYFQ-WZTVWXICSA-N
SMILES: CC(NC1=C(C(C(O)=O)=C(I)C(NC(C)=O)=C1I)I)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC
Biological Activity: Diatrizoate meglumine (Diatrizoic acid meglumine) is an iodinated contrast agent. Diatrizoate meglumine induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoate meglumine induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoate meglumine can be used for research on contrast-induced acute kidney injury (ci-aki)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Diatrizoate meglumine | 99.72% | Diatrizoate meglumine (Diatrizoic acid meglumine) is an iodinated contrast agent. Diatrizoate meglumine induces intracellular calcium homeostasis dysregulation, activates calpain and caspase-12, and activates the executor caspase-3, inducing cell apoptosis. Diatrizoate meglumine induces mitophagy, oxidative stress, and TNFα secretion/inflammatory responses, while inhibiting mitochondrial respiratory function. Diatrizoate meglumine can be used for research on contrast-induced acute kidney injury (ci-aki). | ||||||||||||||||||||
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