2365325-67-1

C5aR1 antagonist 1 Chemical Structure
2365325-67-1

Chemical Structure

C5aR1 antagonist 1

  • CAS No.: 2365325-67-1
  • Formula:C28H27F4N3O
  • Molecular Weight:497.53

InChIKey: IUTHEOCJFAFDRT-UHFFFAOYSA-N

SMILES: O=C1N(CC2=C(C(F)(F)F)C=CC=C2)C3=C(CN1C4CCN(CC4)C5=C(C)C=CC=C5F)C=CC=C3

Biological Activity: C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 (C5aR1) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-163378 		C5aR1 antagonist 1 C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 (C5aR1) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases.
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