2250440-41-4
2250440-41-4
Chemical Structure
Vilobelimab
Synonym(s): CaCP-29, IFX-1
- CAS No.: 2250440-41-4
- Formula:N/A
- Molecular Weight:(145.88 kDa)
IUPAC Name: 6-chloro-3-fluoro-4-methylpyridin-2-amine
SMILES: [Vilobelimab]
Biological Activity: Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vilobelimab | 99.777% | Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc. | ||||||||||||||||||||
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References
- [1]. Michael Bauer, et al. Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study). Crit Care Explor. 2021 Nov 17;3(11):e0577. [Content Brief]
