147516-85-6
Chemical Structure
C-Reactive Protein (CRP) (174-185)
- CAS No.: 147516-85-6
- Formula:C62H93N13O16
- Molecular Weight:1276.48
InChIKey: KODGVWMUDZVVII-FVTMRLMCSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H]1N(C([C@H](CO)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C(CNC(CNC([C@H](CC(C)C)NC([C@H](CC4=CC=C(O)C=C4)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)CCC3)=O)=O)=O)CCC1)=O)=O)=O
Biological Activity: C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma[1][5].
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C-Reactive Protein (CRP) (174-185) | 99.88% | C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma. | ||||||||||||||||||||
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- [1]. Singh SK, et al. Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection. Front Immunol. 2020 Aug 13;11:1812. [Content Brief]
- [5]. Yan X, et al. C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway. Hum Cell. 2021 Sep;34(5):1424-1433. [Content Brief]
Keywords
