Uperolein
Uperolein is a physalaemin-like endecapeptide, produced in the skin of Uperoleia rugosa and Uperoleia marmorata. Uperolein has a spasmodic effect on both the gastrointestinal tract and longitudinal muscles.
For research use only. We do not sell to patients.
- CAS No.: 55601-63-3
- Formula: C57H79N13O16S
- Molecular Weight:1234.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Uperolein (10-100 ng/mL) is a tachykinin analogue, causes or reinforces rhythmic movements and increases the tone in isolated circular and longitudinal muscle of the human gastrointestinal tract from the stomach to the colon[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 55601-63-3
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Molecular Weight 1234.38
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Formula C57H79N13O16S
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Sequence Shortening
{Pyr}-PDPNAFYGLM-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Poulter L, et al. Levitide, a neurohormone-like peptide from the skin of Xenopus laevis. Peptide and peptide precursor cDNA sequences. J Biol Chem. 1988 Mar 5;263(7):3279-83. [Content Brief]
[2]. Anastasi A, et al. Structure of uperolein, a physalaemin-like endecapeptide occurring in the skin of Uperoleia rugosa and Uperoleia marmorata. Experientia. 1975 Apr 15;31(4):394-5. [Content Brief]
[3]. Zappia L, et al. Effects of natural analogues of substance P on the motility of human gastrointestinal tract in vitro. J Pharm Pharmacol. 1978 Sep;30(9):593-4. [Content Brief]
[4]. Bertaccini G, et al. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Uperolein Related Classifications
HY-P2793 Related Classifications
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