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(S)-pMeO-Bz-SF

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-184117A
    (S)-pMeO-Bz-SF

    		Drug Isomer Ser/Thr Protease Others
    (S)-pMeO-Bz-SF, the S isomer of pMeO-Bz-SF (HY-184117A), is a potent covalent serine hydrolase inhibitor with an α-chymotrypsin IC50 of 2.965 μM. (S)-pMeO-Bz-SF covalently modifies α-chymotrypsin residues Ser195, Tyr146, and Ser190. (S)-pMeO-Bz-SF exhibits stereoselective inhibitory activity against α-chymotrypsin .
    (S)-pMeO-Bz-SF
  • HY-184117
    pMeO-Bz-SF

    		Ser/Thr Protease Others
    pMeO-Bz-SF is a covalent, stereoselective α-chymotrypsin inhibitor with an IC50 value of 133 nM. The (R)-enantiomer of pMeO-Bz-SF ((R)-pMeO-Bz-SF (HY-184117B)) inhibits α-chymotrypsin with an IC50 of 101 nM. The (S)-enantiomer of pMeO-Bz-SF ((S)-pMeO-Bz-SF (HY-184117A)) shows low activity against α-chymotrypsin, with an IC50 of 2965 nM .
    pMeO-Bz-SF

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