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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
1,4-DHP
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "1,4-DHP" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity .
Cat. No.: HY-W017960
CAS No.: 1149-23-1
Synonyms: Et-HE; 1,4-DHP
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Research Areas:
Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of G6PD and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .
Cat. No.: HY-W017960R
CAS No.: 1149-23-1
Synonyms: Et-HE (Standard); 1,4-DHP (Standard)
Target:
Research Areas:
Diludine (Standard) is the analytical standard of Diludine (HY-W017960). This product is intended for research and analytical applications. Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of G6PD and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .
Cat. No.: HY-135218
CAS No.: 27296-05-5
Target:
Research Areas:
AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity .
Synonyms: (S)-Niguldipine hydrochloride
Target:
Research Areas:
(+)-Niguldipine hydrochloride is a 1,4-DHP receptor ligand associated with L-type Ca 2+ channels (with Ki values of 85 pmol/L in guinea pig skeletal muscle, 140 pmol/L in brain, and 45 pmol/L in heart) as well as an α1-adrenergic receptor ligand (with a Ki value of 78 nmol/L). (+)-Niguldipine hydrochloride shows much higher binding selectivity for α1α-adrenergic receptors than for α1B-adrenergic receptors. (+)-Niguldipine hydrochloride can be used in studies related to hypertension .
Cat. No.: HY-137203
CAS No.: 113165-32-5
Target:
Research Areas:
(+)-Niguldipine is a 1,4-DHP receptor ligand associated with L-type Ca 2+ channels (with Ki values of 85 pmol/L in guinea pig skeletal muscle, 140 pmol/L in brain, and 45 pmol/L in heart) as well as an α1-adrenergic receptor ligand (with a Ki value of 78 nmol/L). (+)-Niguldipine shows much higher binding selectivity for α1α-adrenergic receptors than for α1B-adrenergic receptors. (+)-Niguldipine can be used in studies related to hypertension .
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Protocols
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