2 Results for "

ZOL 446 disodium

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ZOL 446 disodium" in MCE Product Catalog:

Cat. No.: HY-13777B
CAS No.: 165800-07-7
Synonyms: ZOLedronate disodium tetrahydrate; CGP 42446 disodium tetrahydrate; CGP42446A disodium tetrahydrate; ZOL 446 disodium tetrahydrate
Research Areas:  

Metabolic Disease Cancer

Zoledronic Acid (Zoledronate) disodium tetrahydrate is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid disodium tetrahydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid disodium tetrahydrate also has anti-cancer effects .
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Cat. No.: HY-13777C
CAS No.: 131654-46-1
Synonyms: CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium
Target:  

Apoptosis

Research Areas:  

Cancer

Zoledronate (CGP 42446) disodium is a potent bisphosphonate that effectively inhibits osteoclastogenesis, reducing bone turnover and stabilizing the bone matrix. Zoledronate disodium has demonstrated notable effectiveness in managing Paget's disease of bone by suppressing metabolic activity and alleviating bone pain. Zoledronate disodium is being investigated in the ongoing ZiPP trial for its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also exhibits diverse anti-tumor effects in osteosarcoma, further highlighting its multifunctional therapeutic applications.
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