Zoledronate disodium
Zoledronate (CGP 42446) disodium is a potent bisphosphonate that effectively inhibits osteoclastogenesis, reducing bone turnover and stabilizing the bone matrix. Zoledronate disodium has demonstrated notable effectiveness in managing Paget's disease of bone by suppressing metabolic activity and alleviating bone pain. Zoledronate disodium is being investigated in the ongoing ZiPP trial for its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also exhibits diverse anti-tumor effects in osteosarcoma, further highlighting its multifunctional therapeutic applications.
For research use only. We do not sell to patients.
- CAS No.: 131654-46-1
- Formula: C5H8N2Na2O7P2
- Molecular Weight:316.05
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 131654-46-1
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Molecular Weight 316.05
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Formula C5H8N2Na2O7P2
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SMILES
O=P(O)(C(CN1C=NC=C1)(P(O[Na])(O[Na])=O)O)O
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Synonyms
CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zoledronate disodium Related Classifications
HY-13777C Related Classifications
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