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16275-44-8

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5-Acetamide-Butenolide
5-Acetamide-Butenolide
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Cat. No.: HY-W402074
CAS No.: 16275-44-8
Synonyms: Butenolide
Category:  

Alkaloids Other Alkaloids Poaceae Plants Festuca arundinacea Schreb.

Target:  

Mitochondrial Metabolism Reactive Oxygen Species (ROS)

5-Acetamide-Butenolide (Butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells .
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