1 Result for "

2059921-60-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2059921-60-5" in MCE Product Catalog:

Cat. No.: HY-N17639
CAS No.: 2059921-60-5
Regiafuran C is a compound with both TGF-βRI inhibitory and anti-fibrotic activities. Regiafuran C effectively inhibits renal fibrosis by binding to TGF-βRI and interfering with the TGF-β/Smad and Wnt/β-catenin signaling pathways. Regiafuran C also exhibits free radical scavenging activity, but shows no anti-inflammatory activity in PGE2 competitive enzyme immunoassays. The ability of Regiafuran C to specifically block the Smad3-TGF-βRII interaction and inhibit fibrotic processes allows its use in renal fibrosis research .
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