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870225-11-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "870225-11-9" in MCE Product Catalog:

Cat. No.: HY-160708
CAS No.: 870225-11-9
Target:  

Tie

Research Areas:  

Cancer

Tie2 kinase inhibitor 3 (compound 63) is a potent Tie-2 kinase inhibitor with good oral activity (IC50=30 nM). Tie2 kinase inhibitor 3 inhibits phosphorylation and signaling of Tie-2 by competing with the ATP binding site of Tie-2 kinase. This inhibition affects the stability and maturity of blood vessels, which has an impact on tumor angiogenesis. Tie2 kinase inhibitor 3 can be used to restrict tumor growth and regulate angiogenesis .
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