Tie2 kinase inhibitor 3
Tie2 kinase inhibitor 3 (compound 63) is a potent Tie-2 kinase inhibitor with good oral activity (IC50=30 nM). Tie2 kinase inhibitor 3 inhibits phosphorylation and signaling of Tie-2 by competing with the ATP binding site of Tie-2 kinase. This inhibition affects the stability and maturity of blood vessels, which has an impact on tumor angiogenesis. Tie2 kinase inhibitor 3 can be used to restrict tumor growth and regulate angiogenesis.
For research use only. We do not sell to patients.
- CAS No.: 870225-11-9
- Formula: C29H30F4N8O2
- Molecular Weight:598.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 870225-11-9
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Molecular Weight 598.59
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Formula C29H30F4N8O2
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SMILES
O=C(C1=CC(OC2=C(C3=NC(NC)=NC=N3)C=CC=N2)=CC=C1F)NC4=CC(C(F)(F)F)=CC=C4N(CCCN(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tie2 kinase inhibitor 3 Related Classifications
HY-160708 Related Classifications
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