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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
155 Results for "
A-7
" in MedChemExpress (MCE) Product Catalog:
Products (155)
155 Results for "A-7" in MCE Product Catalog:
28
28 Publications Verification
Target:
Áreas de investigación:
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings .
1
1 Cited Publications
Referencia número: HY-N2481
No. CAS: 36948-76-2
Synonyms: Oroxyloside; Oroxylin A-7-O-β-D-glucuronide
1
1 Cited Publications
Referencia número: HY-P990211
Target:
Áreas de investigación:
1
1 Cited Publications
Referencia número: HY-155659
Pureza: 99.86%
Target:
Áreas de investigación:
4A7C-301 is a blood-brain barrier-permeable Nurr1 agonist, with IC50 values of 48.22 nM and 107.71 nM for binding to Nurr1-LBD in the [ 3H]-CQ competition assay and TR-FRET assay, respectively. The EC50 of 4A7C-301 for activating Nurr1 transcriptional activity is 6.53 μM, and its EC50 in N27-A dopaminergic cells is approximately 0.2 μM. 4A7C-301 binds directly to Nurr1-LBD, enhances the transcriptional function of Nurr1, and restores the reduction of Nurr1 protein induced by MPP + or αSyn. 4A7C-301 alleviates oxidative stress and mitochondrial dysfunction, protects midbrain dopaminergic neurons, inhibits microglial activation, and restores impaired autophagic flux. 4A7C-301 can be used in studies related to neuroprotection and Parkinson's disease .
1
1 Cited Publications
Referencia número: HY-P990209
Target:
Áreas de investigación:
Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
1
1 Cited Publications
Referencia número: HY-P701139A
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14
Referencia número: HY-172236
No. CAS: 1020634-41-6
Synonyms: BNC210; IW-2143
Target:
Áreas de investigación:
Soclenicant (BNC210) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. Soclenicant exhibits acute anxiolytic activity in rodent models of anxiety. Soclenicant inhibits rat and human α7 nAChR currents (in stably transfected cell lines) induced by acetylcholine, nicotine, choline, and the a7-specific agonist PNU-282987 (HY-12560A) with IC50 values in the range of 1.2 to 3 μM. Soclenicant can be used in studies of anxiety, trauma, and stressor-related disorders .
Target:
Áreas de investigación:
KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases .
Áreas de investigación:
Gibberellins A4/A7 induces stimulation of tracheid production in the terminal shoot of intact plants is mediated through an increase in the IAA level in the cambial region .
Target:
Referencia número: HY-P991742
Synonyms: 15A7.5; ETx-22 Antibody
Target:
Áreas de investigación:
Synonyms: Ophobolin A
Target:
Áreas de investigación:
A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer .
Referencia número: HY-P11286
No. CAS: 632358-46-4
Target:
Áreas de investigación:
Referencia número: HY-N10799
No. CAS: 82475-02-3
Target:
Referencia número: HY-RS13030
Target:
Áreas de investigación:
Slc16a7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc16a7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-N14450
No. CAS: 139542-55-5
Category:
Target:
Referencia número: HY-N15420
No. CAS: 18361-47-2
Category:
Target:
Referencia número: HY-159009
No. CAS: 1593654-46-6
Áreas de investigación:
MS7 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT). NAMPT is overexpressed in many cancer cells to meet the continuous replenishment of NAD + required for rapid proliferation. MS7, as a NAMPT target protein ligand, can be used to synthesize PROTAC A7, which is an effective NAMPT degrader. MS7 can be used in cancer research .
Referencia número: HY-N2481R
No. CAS: 36948-76-2
Synonyms: Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
