1593654-46-6
1593654-46-6
Chemical Structure
MS7
- CAS No.: 1593654-46-6
- Formula:C24H27N5O2S2
- Molecular Weight:481.63
InChIKey: LKHGLZDYVMMQOY-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(NC(NCC2=CC=CN=C2)=S)C=C1)(N3CCN(CC3)CC4=CC=CC=C4)=O
Biological Activity: MS7 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT). NAMPT is overexpressed in many cancer cells to meet the continuous replenishment of NAD+ required for rapid proliferation. MS7, as a NAMPT target protein ligand, can be used to synthesize PROTAC A7, which is an effective NAMPT degrader. MS7 can be used in cancer research[1].
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MS7 | MS7 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT). NAMPT is overexpressed in many cancer cells to meet the continuous replenishment of NAD+ required for rapid proliferation. MS7, as a NAMPT target protein ligand, can be used to synthesize PROTAC A7, which is an effective NAMPT degrader. MS7 can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
