5928-26-7
Chemical Structure
Sissotrin
Synonym(s): Biochanin A 7-glucoside; Sissonin
- CAS No.: 5928-26-7
- Formula:C22H22O10
- Molecular Weight:446.40
IUPAC Name: 5-hydroxy-3-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: LFEUICHQZGNOHD-RECXWPGBSA-N
SMILES: O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC(O)=C13
Biological Activity: Sissotrin (Biochanin A 7-glucoside; Sissonin) is an orally active isoflavone glycoside natural product found in Leguminosae plants, with weak antibacterial activity. Sissotrin exacerbates the increase in blood glucose after glucose loading. Sissotrin is used in studies related to glucose metabolism[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sissotrin | 98.46% | Sissotrin (Biochanin A 7-glucoside; Sissonin) is an orally active isoflavone glycoside natural product found in Leguminosae plants, with weak antibacterial activity. Sissotrin exacerbates the increase in blood glucose after glucose loading. Sissotrin is used in studies related to glucose metabolism. | ||||||||||||||||||||
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References
- [1]. Vitor RF, et al. Flavonoids of an extract of Pterospartum tridentatum showing endothelial protection against oxidative injury. Journal of ethnopharmacology. 2004 Aug;93(2-3):363-70.
- [2]. Paulo A, et al. The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats. Phytotherapy research : PTR. 2008 Apr;22(4):539-43.
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[3]. Tsamo D L F, et al. Semisynthetic Derivatives of Sissotrin Isolated from Trifolium baccarinii (Fabaceae) and Evaluation of Their Antibacterial Activities. Advances in Biological Chemistry, 2024, 14: 27-39.
- [4]. Sordon S, et al. Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A. Molecules (Basel, Switzerland). 2017 Jan 03;22(1):81.
