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Cat. No.: HY-N7683

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Prunetin 5-O-β-D-glucopyranoside

Prunetin 5-O-β-D-glucopyranoside is an isoflavone. Prunetin 5-O-β-D-glucopyranoside can be isolated from the pedicels of Prunus avium and Prunus cerasus. Prunetin 5-O-β-D-glucopyranoside acts as a non-competitive α-glucosidase inhibitor, with a IC₅₀ of 56.05 μg/mL and a K_i of 121 μg/mL against Saccharomyces cerevisiae α-glucosidase. Prunetin 5-O-β-D-glucopyranoside can be used in studies related to type 2 diabetes.

For research use only. We do not sell to patients.

CAS No.: 89595-66-4
Formula: C₂₂H₂₂O₁₀
Molecular Weight:446.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Prunetin 5-O-β-D-glucopyranoside Chemical Structure

CAS No.: 89595-66-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

α‑glucosidase

56.05 μg/mL (IC₅₀)

In Vitro

Prunetin 5-O-β-D-glucopyranoside (0.5-100 μg/mL; 15 min pre-incubation with enzyme, 10 min incubation with substrate) acts as an uncompetitive inhibitor of α-glucosidase from Saccharomyces cerevisiae with an IC₅₀ of 56.05 μg/mL and a K_i of 121 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 89595-66-4
Molecular Weight 446.40
Formula C₂₂H₂₂O₁₀
SMILES

O=C1C(C2=CC=C(O)C=C2)=COC3=CC(OC)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C13
Structure Classification
- Flavonoids
- Isoflavones
- Phenols
- Monophenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Şöhretoğlu D, et, al. α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1062-1070. [Content Brief]

[2]. Khalid S A, et, al. Prunetin 5-O-β-d-glucopyranoside, an isoflavone from the peduncle of Prunus avium and P. cerasus[J]. Phytochemistry, 1989, 28(5): 1560-1561.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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