Prunetin 5-O-β-D-glucopyranoside 

Prunetin 5-O-β-D-glucopyranoside is an isoflavone. Prunetin 5-O-β-D-glucopyranoside can be isolated from the pedicels of Prunus avium and Prunus cerasus. Prunetin 5-O-β-D-glucopyranoside acts as a non-competitive α-glucosidase inhibitor, with a IC₅₀ of 56.05 μg/mL and a K_i of 121 μg/mL against Saccharomyces cerevisiae α-glucosidase. Prunetin 5-O-β-D-glucopyranoside can be used in studies related to type 2 diabetes^[1][2].

Prunetin 5-O-β-D-glucopyranoside (0.5-100 μg/mL; 15 min pre-incubation with enzyme, 10 min incubation with substrate) acts as an uncompetitive inhibitor of α-glucosidase from Saccharomyces cerevisiae with an IC₅₀ of 56.05 μg/mL and a K_i of 121 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

446.40

C₂₂H₂₂O₁₀

89595-66-4

O=C1C(C2=CC=C(O)C=C2)=COC3=CC(OC)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C13

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Şöhretoğlu D, et, al. α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1062-1070.  [Content Brief]

  [2]. Khalid S A, et, al. Prunetin 5-O-β-d-glucopyranoside, an isoflavone from the peduncle of Prunus avium and P. cerasus[J]. Phytochemistry, 1989, 28(5): 1560-1561.