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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
ADC human IgG1
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "ADC human IgG1" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-164152A
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1 Cited Publications
Cat. No.: HY-164152
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1 Cited Publications
Cat. No.: HY-P99271
CAS No.: 1418628-81-5
Synonyms: Anti-human F3 Recombinant Antibody
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Cat. No.: HY-164153
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Cat. No.: HY-P99234
CAS No.: 2234335-84-1
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MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .
Cat. No.: HY-P991041
CAS No.: 2650574-80-2
Synonyms: Anti-SEZ6 Antibody (SC17); ABBV-011 antibody; ABBV-706 antibody
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Cat. No.: HY-164957
CAS No.: 2764774-91-4
Synonyms: SGN-B6A; PF-08046047
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SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug (HY-P990764), and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE (HY-15162) .
Cat. No.: HY-P990764
CAS No.: 2764774-90-3
Synonyms: SGN-B6A antibody
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Cat. No.: HY-164668
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ADC Control Human IgG1-SN-38 is an isotype control of ADC Human IgG1-SN-38. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946).
Cat. No.: HY-164154
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Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487
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Cat. No.: HY-164669
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ADC Control Human IgG1-DM4 is an isotype control of ADC Human IgG1-DM4. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is SPDB-DM4 (HY-12460).
Cat. No.: HY-P99233
CAS No.: 921618-45-3
Synonyms: HuMax-TAC
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Cat. No.: HY-P991197
Synonyms: LM-305 antibody; AZD-0305 antibody
Cat. No.: HY-P99970
CAS No.: 1615697-16-9
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Cat. No.: HY-P99230
CAS No.: 1639820-81-7
Cat. No.: HY-P991699
CAS No.: 3035710-69-8
Synonyms: AZD9829 antibody; INT-020
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
