Alkyne Cholesterol

By Targets:	Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (6) Drug Derivative (1) Liposome (1) PPAR (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (4)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (1) Alkynes (3)
Oligonucleotides:	Pegylated Lipids (2) Cholesterol (1)

Targets Recommended: Acyltransferase

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-151705

**Alkyne Cholesterol** 2 Publications Verification	Liposome	Metabolic Disease
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-N0364

Falcarindiol 3 Publications Verification	Apoptosis Autophagy PPAR	Infection Metabolic Disease Inflammation/Immunology Cancer
Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties . Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-174924

Cholesterol-PEG3-azide	Biochemical Assay Reagents	Others
Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-171562

Cholesterol-SA-PEG2000-Azide	Biochemical Assay Reagents	Metabolic Disease
Cholesterol-SA-PEG2000-Azide is a lipid that can be used for drug delivery. Cholesterol-SA-PEG2000-Azide contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG2000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

HY-158636

19-Alkyne cholesterol 19-Ethynyl Cholesterol	Drug Derivative	Others
19-Alkyne Cholesterol is an alkyne derivative of cholesterol. It has been used to track cholesterol localization and subcellular distribution in cells.

HY-137018

27-Alkyne cholesterol	Biochemical Assay Reagents	Others
27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

HY-174924A

Cholesterol-PEG8-azide	Biochemical Assay Reagents	Others
Cholesterol-PEG8-azide is a PEG derivative composed of Cholesterol, 8 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-N15960

Photoclick cholesterol II	Biochemical Assay Reagents	Others
Photoclick cholesterol II is a sterol lipid Cholesterol (HY-N0322) analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group.

HY-173385

Cholesteryl-PEG1000-Azide	Biochemical Assay Reagents	Metabolic Disease
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	상품명	Type

HY-151705

**Alkyne Cholesterol** 2 Publications Verification	Biochemical Assay Reagents
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-174924

Cholesterol-PEG3-azide	Biochemical Assay Reagents
Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-171562

Cholesterol-SA-PEG2000-Azide	Biochemical Assay Reagents
Cholesterol-SA-PEG2000-Azide is a lipid that can be used for drug delivery. Cholesterol-SA-PEG2000-Azide contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG2000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

HY-174924A

Cholesterol-PEG8-azide	Biochemical Assay Reagents
Cholesterol-PEG8-azide is a PEG derivative composed of Cholesterol, 8 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-173385

Cholesteryl-PEG1000-Azide	Biochemical Assay Reagents
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N0364

Falcarindiol 3 Publications Verification	Infection Natural Products Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Metabolic Disease Umbelliferae Plants Inflammation/Immunology Disease Research Fields Source Classification	Apoptosis Autophagy PPAR
Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties . Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N15960

Photoclick cholesterol II	Lipid	Biochemical Assay Reagents
Photoclick cholesterol II is a sterol lipid Cholesterol (HY-N0322) analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group.

Cat. No.	상품명		Classification

HY-151705

**Alkyne Cholesterol** 2 Publications Verification		Alkynes Labeling and Fluorescence Imaging
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-158636

19-Alkyne cholesterol 19-Ethynyl Cholesterol		Alkynes
19-Alkyne Cholesterol is an alkyne derivative of cholesterol. It has been used to track cholesterol localization and subcellular distribution in cells.

HY-137018

27-Alkyne cholesterol		Alkynes
27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

HY-173385

Cholesteryl-PEG1000-Azide		Azide
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	상품명		Classification

HY-151705

**Alkyne Cholesterol** 2 Publications Verification		Cholesterol
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-171562

Cholesterol-SA-PEG2000-Azide		Pegylated Lipids
Cholesterol-SA-PEG2000-Azide is a lipid that can be used for drug delivery. Cholesterol-SA-PEG2000-Azide contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG2000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

HY-173385

Cholesteryl-PEG1000-Azide		Pegylated Lipids
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Inhibitors & Agonists

Biochemical Assay Reagents

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Click Chemistry

Oligonucleotides

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